PRODUCT DETAILS

About Basugine 100IU/ml Injection

INSULIN GLARGINE is a long-acting insulin that contains insulin glargine. This is a modified insulin, very similar to human insulin. Human insulin is the name which describes synthetic (human-made) insulin which is laboratory grown to mimic the insulin in humans. INSULIN GLARGINE is used to treat diabetes mellitus in adults, adolescents and children aged 2 years and above. Diabetes mellitus is a disease where your body does not produce enough insulin to control the level of blood sugar. INSULIN GLARGINE has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting, and is designed to act uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. Treatment with INSULIN GLARGINE helps to prevent complications from your diabetes. Do not use INSULIN GLARGINE to treat diabetic ketoacidosis (too much of acids in the blood).

Uses of Basugine 100IU/ml Injection

Type 1 diabetes mellitus, Type 2 diabetes mellitus

Medicinal Benefits of Basugine 100IU/ml Injection

INSULIN GLARGINE has a long and steady blood-sugar-lowering action. Long acting insulin takes about 2 hours to start acting, and is designed to act uniformly so that there is no peak activity as such. The duration of long acting insulin is up to 24 hours. This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the live. INSULIN GLARGINE helps in improving the glycaemic control which in turn decreases the risk of progression of complications of diabetes like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, INSULIN GLARGINE can be safely prescribed to the diabetic mother in the pregnancy as well as lactation stage.

Directions for Use

INSULIN GLARGINE is injected under the skin (subcutaneously). Do NOT inject INSULIN GLARGINE in a vein. You need one injection of INSULIN GLARGINE every day, at the same time of the day. If you are not well trained to self-administer INSULIN GLARGINE, ask healthcare professional to administer it. Procedure for self-injecting insulin: • You should wash your hand first before injecting insulin. • Then roll the insulin bottle and wipe the bottle top. • Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed. • Push the needle into the bottle and push the syringe plunger down. • Now once again pull the plunger down to an appropriate number of units as prescribed by the doctor. • Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin and push the needle into the skin and then push the plunger in. • The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected. • After injecting the insulin pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Side Effects of Basugine 100IU/ml Injection

Like all medicines, INSULIN GLARGINE can cause side effects, although not everybody gets them. The following side effects may occur which can be a sign of low blood sugar or hypoglycaemia like cold sweat, cool pale skin, nervousness, anxious feeling, unusual tiredness or weakness, confusion, difficulty in concentration, drowsiness, excessive hunger, temporary vision changes, headache, nausea, and increased pulse or heartbeat (palpitation). Skin and allergic reactions at the injection site may occur with the sign of reddening, unusually intense pain when injecting, itching, hives, swelling, or inflammation. This can spread around the injection site. Most minor reactions to insulins usually disappear in a few days to a few weeks. Tell a doctor straight away if you notice signs of a severe allergic reaction. Everyone doesn't need to experience the above side effects.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

INSULIN GLARGINE is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients who are at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may either increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. INSULIN GLARGINE may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take INSULIN GLARGINE if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug Interactions

Drug-Drug Interaction:

 INSULIN GLARGINE may have an interaction with all other antidiabetic pills (sitagliptin), blood sugar enhancer (diazoxide), blood pressure-lowering pills (metoprolol, clonidine), antidepressants (lithium, fluoxetine), pain killers (aspirin, pentoxifylline, propoxyphene), anti TB drug (isoniazid), growth hormone (somatropin), thyroid hormone-related drugs (levothyroxine), antipsychotic medicines (phenothiazine, clozapine, olanzapine), anti-cholesterol drugs (fenofibrate), anti-asthmatic (epinephrine, salbutamol, terbutaline), female hormones like oestrogens and progestogens.

Drug-Disease Interaction:

 INSULIN GLARGINE should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).

Safety Advice

ALCOHOL

You are recommended not to consume alcohol along with INSULIN GLARGINE to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

PREGNANCY

INSULIN GLARGINE can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery. Please consult your doctor before taking INSULIN GLARGINE.

BREAST FEEDING

INSULIN GLARGINE can be given safely to nursing mothers but only under the supervision of a physician. Physician may adjustments in your insulin doses and your diet.

DRIVING

Drive with caution, INSULIN GLARGINE usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

LIVER

INSULIN GLARGINE to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

KIDNEY

INSULIN GLARGINE to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.