PRODUCT DETAILS

About Adyom LS 75mg/40mg Capsule

ESOMEPRAZOLE+LEVOSULPIRIDE belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus), this causes acidity, pain and heartburn. 

Uses of Adyom LS 75mg/40mg Capsule

Gastro-oesophageal reflux disease.

Medicinal Benefits of Adyom LS 75mg/40mg Capsule

ESOMEPRAZOLE+LEVOSULPIRIDE belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). ESOMEPRAZOLE+LEVOSULPIRIDE is a combination of two drugs, namely: Esomeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby prevents backflow of food and acid into the mouth. Together, ESOMEPRAZOLE+LEVOSULPIRIDE helps in preventing acid reflux, thereby provides relief from acidity and heartburn.

Directions for Use

Take ESOMEPRAZOLE+LEVOSULPIRIDE 1hour prior food. Swallow ESOMEPRAZOLE+LEVOSULPIRIDE as a whole with a glass of water; do not chew, or crush the tablet. Depending on your medical condition, your doctor will decide how long you need to take ESOMEPRAZOLE+LEVOSULPIRIDE.

Side Effects of Adyom LS 75mg/40mg Capsule

Like all medicines, ESOMEPRAZOLE+LEVOSULPIRIDE can also cause side-effects, although not everybody experiences them. Headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting are the common side-effects of ESOMEPRAZOLE+LEVOSULPIRIDE. Talk to your doctor if you experience any of these side-effects persistently.

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take ESOMEPRAZOLE+LEVOSULPIRIDE if you are allergic to any of its contents; if you are taking nelfinavir (anti-HIV); if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking ESOMEPRAZOLE+LEVOSULPIRIDE if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long term treatment, ESOMEPRAZOLE+LEVOSULPIRIDE may increase the risk of bone fractures. Do not take ESOMEPRAZOLE+LEVOSULPIRIDE if you are pregnant or breastfeeding. ESOMEPRAZOLE+LEVOSULPIRIDE may cause dizziness and drowsiness, so drive only if you are alert. ESOMEPRAZOLE+LEVOSULPIRIDE should not be given to children as the safety have not been established. Avoid consuming alcohol along with ESOMEPRAZOLE+LEVOSULPIRIDE as it could lead to increased drowsiness and can elevate the production of stomach acid. 

Drug Interactions

Drug-Drug Interaction:

ESOMEPRAZOLE+LEVOSULPIRIDE may have interaction with painkillers (aspirin, naproxen), anti-HIV (atazanavir), blood thinner (clopidogrel, warfarin, cilostazol), anti-fungal (ketoconazole, itraconazole, voriconazole), anti-cancer (erlotinib, methotrexate), anti-depressant (citalopram, imipramine, clomipramine, duloxetine), anti-anxiety (diazepam), anti-convulsant (phenytoin), gastroprokinetic agent (cisapride), a drug used to treat heart problems (digoxin), immunosuppressant (tacrolimus), anti-tuberculosis (rifampicin).

Drug-Disease Interaction:

ESOMEPRAZOLE+LEVOSULPIRIDE may have interactions with epilepsy, mania, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, hypomagnesemia (low levels of magnesium).

Safety Advice

ALCOHOL

• Avoid consumption of alcohol while taking ESOMEPRAZOLE+LEVOSULPIRIDE. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

PREGNANCY

• ESOMEPRAZOLE+LEVOSULPIRIDE should not be taken if you are pregnant. Consult your doctor before taking ESOMEPRAZOLE+LEVOSULPIRIDE if you are pregnant.

BREAST FEEDING

• ESOMEPRAZOLE+LEVOSULPIRIDE may pass into breast milk. Consult your doctor before taking ESOMEPRAZOLE+LEVOSULPIRIDE if you are breastfeeding.

DRIVING

• ESOMEPRAZOLE+LEVOSULPIRIDE may cause dizziness, drowsiness and blurred vision. Do not drive or operate machinery unless you are alert.

LIVER

• ESOMEPRAZOLE+LEVOSULPIRIDE should not be used in patients with hepatic impairment. Consult your doctor before taking ESOMEPRAZOLE+LEVOSULPIRIDE if you have a liver impairment or any concerns regarding this.

KIDNEY

• Dose adjustment may be needed. Consult your doctor before taking ESOMEPRAZOLE+LEVOSULPIRIDE if you have kidney impairment or any concerns regarding this.